| DT McTelvin Agim (DEN) | 1 game (0 starts); 14 snaps vs. Cincinnati, 1 ST snap | 7 games (0 starts); 4 tackles (2 solo), 1.5 SKS, 1 PDEF |
| QB Brandon Allen (CIN) | DNP at Denver | 4 games (0 starts); 2-of-4, 13 yards, 1 TD, 5 carries, -4 yards |
| RB Alex Collins (SEA) | DNP at Los Angeles Rams: reserve/COVID-19 | 11 games (6 starts); 108 carries, 411 yards, 2 TDs, 9 receptions, 87 yards, 1 fumble |
| S Kamren Curl (WAS) | DNP at Philadelphia: reserve/COVID-19 | 13 games (11 starts); 75 tackles (48 solo), 1.0 SK, 4 PDEF, 1 FR |
| QB Feleipe Franks (ATL) | 1 game (0 starts); 1 snap at San Francisco | 9 games (0 starts); 0-for-1, 1 interception, 3 carries, 6 yards |
| LB De'Jon Harris (WAS) | 1 game (0 starts); 22 snaps at Philadelphia; 22 ST snaps; 1 tackle (1 solo) | 2 games (0 starts); 1 tackle (1 solo) |
| TE Hunter Henry (NE) | 1 game (1 starts); 61 snaps at Indianapolis, 6 ST snaps; 6 receptions, 77 yards, 2 TDs | 14 games (8 starts); 41 receptions, 471 yards, 9 TDs |
| WR Cody Hollister (TEN) | 1 game (0 starts); 66 snaps at Pittsburgh, 10 ST snaps; 1 reception, 5 yards | 3 games (1 start); 4 receptions, 33 yards |
| DL Jonathan Marshall (NYJ) | 1 game (0 starts); 30 snaps at Miami, 1 ST snap; 2 tackles (1 solo) | 3 games (0 starts); 2 tackles (1 solo) |
| OL Jason Peters (CHI) | DNP: Inactive vs. Minnesota | 13 games (13 starts) |
| DL Darius Philon (LV) | 1 game (0 starts); 14 snaps vs. Cleveland | 8 games (0 starts); 11 tackles (7 solo), 2 SKs, 2 FRs |
| DL Chris Smith (HOU) | 1 game (0 starts); 27 snaps at Jacksonville; 4 tackles (2 solo), 1 SK | 3 games (0 starts); 4 tackles (2 solo), 1 SK |
| OL Dan Skipper (DET | 1 game (0 starts); 6 snaps vs. Arizona, 6 ST snaps | 1 game (0 starts) |
| TE Jeremy Sprinkle (DAL) | 1 game (1 start); 29 snaps at New York Giants, 12 ST snaps; 2 receptions, 21 yards | 14 games (2 starts); 2 receptions, 21 yards |
| DL Armon Watts (MIN) | 1 game (0 starts); 41 snaps at Chicago, 2 ST snaps | 14 games (7 starts); 31 tackles (13 solo), 5 SKs, 2 FF |
| DE Deatrich Wise Jr. (NE) | 1 game (0 starts); 4 snaps at Indianapolis; 2 tackles (2 solo), 1 SK | 14 games (9 starts); 30 tackles (19 solo), 3 SKs, 4 PDEF, 1 FF |
| RB Jonathan Williams (WAS) | 1 game (0 starts); 17 snaps at Philadelphia; 15 ST snaps; 1 carry, 5 yards | 2 games (0 starts); 5 carries, 21 yards, 1 TD, 1 reception, 19 yards |